One thing to consider is with a wet line vacuum system you want your main line to have a constant slope, or as constant as possible , you want the liquid running in the bottom of the pipe and the air/vacuum on top to achieve good vac transfer. So if your hill is really steep you will want to run across the slope at an angle up the hill even if you have to put a switch back/ zig-zag in the mainline. Also makes it eaiser to run your laterals down hill to the mainline. If you have the potential for 1000 taps I would go with a 1/1-4 line.
Also with a 3/16 system the pumped vacuum is additive or a bonus if you will, I'm not sure how much you would really gain with a wet dry setup.
Nate Hutchins
Nate & Kate's Maple
2022 1000 taps?
3x10 Intensofire
20x36 sugarhouse
CDL 600gph RO
A wife and 2 kids.